Clinical study on the effect of Yi-Gong-San on the prognosis of patients with chronic anemia and sepsis
- Conditions
- Sepsis accompanied by chronic anemia
- Registration Number
- ITMCTR2100004518
- Lead Sponsor
- Baoshan Branch of Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Definitely diagnosed as sepsis related ACD;
(2) Moderate or mild anemia (male :60g/L < Hb < 120g/L, female :60g/L < Hb < 110g/L);
(3) Older than 18 years old;
(4) Volunteered to participate in the clinical trial and signed the informed consent.
(1) Being treated with iron and/or EPO;
(2) Known iron metabolic diseases;
(3) Malignant tumor or immune system disease is found after hospitalization;
(4) Transfusion during hospitalization (to avoid the effects of unnecessary transfusion on hemoglobin and anemia-related parameters);
(5) Other diseases causing anemia (aplastic anemia, iron deficiency anemia, hemolytic anemia, etc.) have been diagnosed before admission;
(6) Significant blood loss (such as gastrointestinal bleeding);
(7) Trauma
(8) Chronic liver failure or chronic renal insufficiency caused by other causes;
(9) Abandonment of treatment.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In-hospital mortality rate;
- Secondary Outcome Measures
Name Time Method HO-1;IFN-?;Hb;SOFA score;IL-17a;sTfR;SI;TNF-a;IL-2;TSAT;Hepcidin;RDW;APACHEII score;IL-4;IL-6;SF;IL-10;TIBC;