Dexmeditomidine as adjuvant to anesthesia
Phase 4
Recruiting
- Conditions
- Intraoperative sedation and analgesia.Thr drug under study will be given as adjuvant to anesthesia to produce sedation and analgesia and reduce the dose of anesthetic agents, analgesic and drugs for neasea & vomiting.U00-U85
- Registration Number
- IRCT20230824059251N1
- Lead Sponsor
- Islamic International Medical College and Wah medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
ASA I &II
Pakistani origin
Exclusion Criteria
No co-morbidity
Non pregnant females
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraoperative sedation and analgesia. Timepoint: beore interventiona and at 1/2 an hour interval and at 2hrs interval. Method of measurement: Ramsay Sedation scale, Visual analogue scale and polymorphism in genes.;Genotyping and Polymorphism in Receptor gene and in enzyme gene. Timepoint: Polymorphism cam be studies both in control and study group in blood sample of 2hsr interval. Method of measurement: Drug concentration will be meausred at 30 min and at 2hrs interval in both groups.
- Secondary Outcome Measures
Name Time Method