MedPath

Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People

Not Applicable
Recruiting
Conditions
Hypertension,Essential
Hypertension
Interventions
Other: Group control
Other: Isometric Exercise
Other: Aerobic Exercise
Registration Number
NCT06282302
Lead Sponsor
Instituto de Cardiologia do Rio Grande do Sul
Brief Summary

Introduction: Adequate blood pressure control is necessary to reduce the risk of mortality from cardiovascular events. The effects of aerobic exercise on systemic arterial hypertension are already well known, however, to date, there is little evidence regarding the effect of an isometric exercise session for the lower limbs on blood pressure levels, especially when performed in elderly hypertensive individuals. Objective: To verify the effect of an isometric or aerobic exercise protocol for the lower limbs on 24-hour ambulatory blood pressure in elderly hypertensive individuals.

Detailed Description

Introduction: Adequate blood pressure control is necessary to reduce the risk of mortality from cardiovascular events. The effects of aerobic exercise on systemic arterial hypertension are already well known, however, to date, there is little evidence regarding the effect of an isometric exercise session for the lower limbs on blood pressure levels, especially when performed in elderly hypertensive individuals. Objective: To verify the effect of an isometric or aerobic exercise protocol for the lower limbs on 24-hour ambulatory blood pressure in elderly hypertensive individuals.

Methods: Thirty-six controlled hypertensive volunteers, aged ≥ 60 years, of both sexes, will be randomly selected based on their medical records. Volunteers will be randomized to perform an isometric wall squat exercise session (n=12 - 4 repetitions of 2 minutes of execution and 2 minutes of rest, performed at a specific angle of the volunteer\'s knee joint - Borg scale of 11 to 13 points - moderate intensity) or an aerobic exercise session on a stationary bike (n=12 - 40 minutes and at moderate intensity stipulated between the range of 50% to 60% of HR reserve and Borg scale of 11 to 13 points - moderate intensity) or a control session without exercise, 40 minutes per session (n=12). 24-hour Ambulatory Blood Pressure Monitoring will be performed pre- and post-session. Statistical analyzes will be performed using the ANOVA test (one way), power of 80% and alpha 95%, SPSS-26.0.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
36
Inclusion Criteria
  • Hypertensive elderly;
  • Both genders;
  • Aged ≥ 60 years;
  • Hypertensive patients on continuous use of antihypertensive medication;
  • Hypertensive who did not practice physical exercise regularly (≥ 2 sessions per week).
Exclusion Criteria
  • Those who presented one of the following issues will be excluded:
  • Diabetes mellitus;
  • Chronic renal failure;
  • Body mass index (BMI) ≥ 35 kg/m2;
  • Coronary artery disease;
  • Heart failure;
  • Any injury to the lower limbs;
  • Smokers.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group controlGroup controlThe control session will consist of keeping the volunteer sitting in a calm, air-conditioned environment for 40 minutes.
Isometric ExerciseIsometric ExerciseThe intervention with isometric exercise for the lower limbs, the volunteers will start in a vertical position, with shoulders and hips in contact with the wall, feet parallel and shoulder-width apart and hands at the sides of the body. Then (second phase), the volunteers, maintaining contact with the wall, squatted and advanced their feet in the desired position until the knee joint angle reached the previously determined value. The third phase referred directly to the isometric effort of the isometric exercise session. For the isometric wall squat exercise session, volunteers will be asked to perform 4 repetitions of 2 minutes, with a 2-minute rest interval in a seated position for adequate rest between each repetition.
Aerobic ExerciseAerobic ExerciseVolunteers will perform 50 minutes of horizontal exercise cycling (brand: pro-user), continuously and at moderate intensity (50% to 60% of HR reserve).
Primary Outcome Measures
NameTimeMethod
24-hour Ambulatory Blood Pressure MonitoringUntil completion of the study, on average 4 months.

Check 24-hour blood pressure levels (24-hour Ambulatory Blood Pressure Monitoring) obtained after an isometric squat session in elderly individuals with SAH and compare BP levels after an exercise session on a stationary bike and the control group.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Institute of Cardiology

🇧🇷

Porto Alegre, RS, Brazil

© Copyright 2025. All Rights Reserved by MedPath