A Pilot Study to Determine a Candidate Protocol for Transcranial Electrical Stimulation in the Treatment of Anxiety

Not Applicable

• Conditions: Anxiety
• Interventions: Device: NeuroConn DC Stimulator Plus, tDCS

• Registration Number: NCT02321891
• Lead Sponsor: University of Eastern Finland

Brief Summary

The investigators examine the efficacy of two different transcranial direct current stimulation (tDCS) stimulation protocols in the treatment of anxiety in an open-label pilot study.

Detailed Description

The investigators examine the efficacy of two different transcranial direct current stimulation (tDCS) stimulation protocols in the treatment of anxiety in an open-label pilot study in patients with chronic pain. The investigators also seek to detect autonomic nervous system changes induced by the tDCS, and develop new methods for the measurement of autonomic nervous system functions.

Study Timeline

• Status Verified: 2014-12
• Study Start: 2014-12
• Study First Submitted: 2014-12-09
• Study First Submitted QC: 2014-12-16
• Last Update Submitted: 2014-12-16
• Study First Posted: 2014-12-22
• Last Update Posted: 2014-12-22
• Primary Completion: 2015-10
• Study Completion: 2015-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Age 18-65 years
• Naïve to tDCS
• Right-handed
• Beck Anxiety Scores >= 26

Exclusion Criteria

• Metal implants inside skull or eye
• Severe skin lesions at the electrode placement area
• History of epilepsy or previous seizures
• Pregnant or breast-feeding
• Pacemaker
• History of intracerebral bleeding during the past six months
• Lifetime DSM-IV diagnosis of bipolar mood disorder or psychotic disorder
• DSM-IV diagnosis for substance abuse or dependence during the past six months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Treatment 1	NeuroConn DC Stimulator Plus, tDCS	NeuroConn DC Stimulator Plus, tDCS treatment protocol no 1
Treatment 2	NeuroConn DC Stimulator Plus, tDCS	NeuroConn DC Stimulator Plus, tDCS treatment protocol no 2

Primary Outcome Measures

Name	Time	Method
Beck Anxiety Inventory	12 days	change in scores of anxiety

Trial Locations

Locations (1)

University of Eastern Finland; 🇫🇮 Kuopio, Finland