A Study to estimate risk of cardiovascular disease in newly diagnosed patients of Psoriasis by utilising blood tests like Fasting Lipid Profile to calculate certain indices like the Atherogenic Index of Plasma
- Conditions
- Health Condition 1: L400- Psoriasis vulgaris
- Registration Number
- CTRI/2023/09/057352
- Lead Sponsor
- IADVL Academy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Newly diagnosed cases of Psoriasis of both genders.
Patients suffering from psoriatic erythroderma. Patients with diseases that can cause secondary hyperlipidemia such as hypothyroidism, diabetes mellitus, nephrotic syndrome, chronic renal insufficiency, obstructive liver disease and connective tissue disorder. Patients on medications such as corticosteroids, retinoids, cyclosporin and lipid lowering agents will be excluded.Patients with diseases that can cause secondary hypolipidemia and hypoproteinemia such as malnutrition, liver failure, malabsorption syndromes, and hyperthyroidism will be excluded.
Patients with diseases that can cause secondary hyperproteinemia will also be excluded.
Patients who are unwilling to give consent to the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Atherogenic Index vs Cardiovascular Risk <br/ ><br>-0.3 – 0.1Low Risk <br/ ><br>0.1 – 0.24Medium Risk <br/ ><br>0.24 High Risk <br/ ><br>Timepoint: Baseline
- Secondary Outcome Measures
Name Time Method ATHEROGENIC COEFFICIENT: ((Total Cholesterol-Serum HDL-c))/(HDL-c)Timepoint: Baseline;CASTELLI RISK INDEX 1: (Total Cholesterol(TC))/(HDL-c)Timepoint: Baseline;CASTELLI RISK INDEX 2: (LDL-c)/(HDL-c)Timepoint: Baseline;COMPREHENSIVE LIPID TETRAD INDEX: [total cholesterol × triglycerides × lipoprotein (a)]/high-density lipoproteinTimepoint: Baseline;FRAMINGHAM RISK SCORETimepoint: Baseline;LAP : WC-58 × TG for women LAP : WC-65 × TG for menTimepoint: Baseline