Comparison Between Clonidine And Dexmedetomidine As Spinal Additive In Prolongation Of Postoperative Analgesia.
- Conditions
- Bilateral inguinal hernia, with obstruction, without gangrene,
- Registration Number
- CTRI/2025/06/089344
- Lead Sponsor
- Sudha Institute of Medical Sciences
- Brief Summary
unless contraindicated, almost all the lower abdomen and lower limb surgeries are done under spinal anaesthesia using hyperbaric bupivacaine. To prolong the sensory and motor blockade duration following spinal anaesthesia various additives has been used historically, here in our study i am going to compare alpha 2 agonist clonidine and dexmedetomidine as a spinal additive in prolonging the duration of spinal analgesia, hemodynamic fluctuations and its effects on sedation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 80
1.Age 20-60yrs 2.ASA grade 1 & 2 3.Willing patients.
1.Uncooperative patients 2.Uncontrolled DM and SHTN 3.Allergy to study drugs 4.Height <150cms 5.Contraindication to spinal anaesthesia 6.Patient refusal 7.Infection at injection site 8.Increased intracranial pressure 9.Indeterminate neurological diseases 10.Coagulopathy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Our primary objective is to evaluate the efficacy of two different drugs of same group (alpha2 adrenergic agonist) clonidine & dexmedetimidine in combination with 0.5% hyperbaric bupivacaine via intrathecal route with regard to the quality of anaesthesia namely time to attain highest sensory and motor blockade, haemodynamic changes and time to first rescue analgesia. WITHIN 24 HOURS
- Secondary Outcome Measures
Name Time Method sedatory effects of both drugs in the postoperative period. 5months
Trial Locations
- Locations (1)
sudha hospitals
🇮🇳Erode, TAMIL NADU, India
sudha hospitals🇮🇳Erode, TAMIL NADU, IndiaDrNantheta RamuPrincipal investigator9003884668nantheta@gmail.com