Characteristics of Rheumatoid Arthritis Patients With Atlantoaxial Synovitis Detected by Plain X-ray and MRI

Not Applicable

Withdrawn

• Conditions: Neck Pain
• Interventions: Radiation: Plain X-ray; Radiation: Magnetic resonance imaging

• Registration Number: NCT02774070
• Lead Sponsor: Assiut University

Brief Summary

This study detects the presence of atlantoaxial joint affection in symptomatic versus asymptomatic rheumatoid arthritis patients revealed by plain X-ray and magnetic resonance imaging of the cervical spine

Detailed Description

Atlantoaxial joint affection in rheumatoid arthritis patients may have life-threatening complications if not detected early. It may not be detected unless it becomes symptomatic. However, asymptomatic atlantoaxial joint affection is not uncommon. Investigators will try to detect atlantoaxial joint affection at an early stage and its relation to symptomatology and other disease criteria. So investigators will use conventional plain X-ray examination combined with magnetic resonance imaging of the cervical spine to detect soft tissue as well as bony changes of this condition.

Study Timeline

• Study First Submitted: 2016-05-11
• Study First Submitted QC: 2016-05-12
• Study First Posted: 2016-05-17
• Study Start: 2016-10
• Primary Completion: 2017-01
• Study Completion: 2017-02
• Status Verified: 2020-01
• Last Update Submitted: 2020-01-11
• Last Update Posted: 2020-01-14

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Rheumatoid arthritis patients complaining or not complaining of atlantoaxial affection symptomatology

Exclusion Criteria

• Pregnant females
• Patients with pacemakers or metallic bony plates.
• Patients that have claustrophobia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Asymptomatic atlantoaxial joint aff.	Plain X-ray	Undergo plain X-ray and magnetic resonance imaging
Symptomatic atlantoaxial joint affection	Plain X-ray	Undergo plain X-ray and magnetic resonance imaging
Symptomatic atlantoaxial joint affection	Magnetic resonance imaging	Undergo plain X-ray and magnetic resonance imaging
Asymptomatic atlantoaxial joint aff.	Magnetic resonance imaging	Undergo plain X-ray and magnetic resonance imaging

Primary Outcome Measures

Name	Time	Method
Prevelance of atlantoaxial joint affection in clinically and laboratory proven rheumatoid arthritis patients	3 months	Prevelance of atlantoaxial joint affection in symptomatic versus asymptomatic rheumatoid arthritis patients