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Clinical Trials/NCT05004051
NCT05004051
Recruiting
Not Applicable

Prospective Registry Study to Collect Imaging and Clinical Data on Patients With Aortic Aneurysm Disease Undergoing Serial Monitoring & Pre and Post Endovascular Repair

ViTAA Medical Solutions8 sites in 2 countries200 target enrollmentDecember 15, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Abdominal Aortic Aneurysms
Sponsor
ViTAA Medical Solutions
Enrollment
200
Locations
8
Primary Endpoint
Composite of aneurysm rupture or critical growth.
Status
Recruiting
Last Updated
7 months ago

Overview

Brief Summary

This is a Prospective Registry study to collect imaging and clinical data both on patients with aortic aneurysm disease undergoing serial monitoring and on patients pre and post-endovascular repair, using ViTAA (The Sponsor) aortic mapping technology.

Detailed Description

This a prospective, multi-center, registry of patients that are being assessed with the ViTAA software. Patients will be enrolled at selected North American centers in the US and Canada. The Registry will enroll patients from the following two populations: * patients who are scheduled and ultimately receive endovascular infrarenal aortic aneurysm repair (EVAR); * patients who do not yet qualify for infrarenal aortic aneurysm repair based on anatomic size criteria who are enrolled in a serial monitoring program.

Registry
clinicaltrials.gov
Start Date
December 15, 2021
End Date
December 31, 2026
Last Updated
7 months ago
Study Type
Observational
Sex
All

Investigators

Sponsor
ViTAA Medical Solutions
Responsible Party
Principal Investigator
Principal Investigator

Dr Mark Farber

Principal Investigator

ViTAA Medical Solutions

Eligibility Criteria

Inclusion Criteria

  • Patient is aged 18 years or over
  • Infrarenal Aortic Aneurysm ≥ 45 mm in diameter.
  • Patient meets on-IFU criteria for endovascular reconstruction

Exclusion Criteria

  • Patient has a known or clinically suspected major connective tissue disorder, autoimmune disorder, vasculitis, or aortic dissection.
  • Patient has renal failure (defined as dialysis dependent or serum creatinine ≥2.0mg/dL or 175umol/L
  • Patients with previous aortic reconstruction in the involved segment.
  • Patients receiving oral or parenteral corticosteroid therapy for other unrelated disease. (Excludes inhaled corticosteroids).
  • Patient has a sensitivity to contrast imaging agents.
  • Patient has aortic dissection.
  • Patient has atrial fibrillation.
  • Patient has arrhythmia.

Outcomes

Primary Outcomes

Composite of aneurysm rupture or critical growth.

Time Frame: 1 year

* Critical growth defined as an increase of \> 0.5 cm in any of the three growth measurements below * Critical growth defined as an increase of \> 0.5 cm in aortic diameter. * Critical growth defined as an increase of \> 0.5 cm in ILT. * Critical growth defined as an increase of \> 0.5 cm in aneurysm sac volume.

Secondary Outcomes

  • CHUM Ancillary Ultrasound Study(1 year)

Study Sites (8)

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