A study to compare the effectiveness of administering ketamine, levo-bupivacaine and a combination of both into the abdominal cavity for reducing post surgical pain in patients after keyhole surgery for gall bladder removal
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2019/07/019969
- Lead Sponsor
- Amala Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of either sex,between age 18 years-70years,ASA physical status 1-3,who are scheduled for laparoscopic cholecystectomy under General Anesthesia and are willing and able to give informed consent will be recruited to the trial
Exclusion Criteria
Patients were excluded if
1.they had a clinical diagnosis of acute pancreatitis
2.acute preoperative pain other than biliary colic
3.chronic pain treatment
4.anti-epileptic therapy
5.history of alcohol or drug addiction
6.severe hepatic or renal impairment
7.allergy to the study drugs
8.cognitive impairment or communication problems
9.pregnant or lactating
10.conversion to open cholecystectomy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24 hour total rescue analgesic (diclofenac +/-tramadol) consumption <br/ ><br>Timepoint: at 24 hours post operatively
- Secondary Outcome Measures
Name Time Method Reduction of postoperative pain scores,Time to first requirement of rescue analgesia, time to unassisted ambulation and Tolerability of the used doses represented by the side effects.Timepoint: At 6h 12h and 24 hours post operatively