Relative Importance of Cardiovascular Risk Factors and Echocardiographic Parameters Affecting Left Atrial Strain
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2,500
- 试验地点
- 1
- 主要终点
- Relative importance of left atrial reservoir strain
研究概览
简要总结
The goal of this observational study is to learn about left atrial reservoir strain in patients with heart failure with preserved ejection fraction. The main questions it aims to answer are:
- Usefullness of LARS as a predictor of high HFA-PEFF diagnostic algorithm scores (≥5)
- The relative importance of LARS in variables including each component of HFA-PEFF and traditional cardiovascular risk factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants with ICD-10 code of heart failure (I50) from August 2021 to July 2022
- •20-year-old or higher age
- •Participants who are available to measure left atrial reservoir strain
排除标准
- •Left ventricular ejection fraction <50%
- •Supraventricular arrhythmia (e.g. atrial flutter/fibrillation, atrial tachycardia)
- •Participants who are given pacemaker or ICD implantation procedure
结局指标
主要结局
Relative importance of left atrial reservoir strain
时间窗: through study completion, an average of 1 year
Relative importance of left atrial reservoir strain among variables, including component of HFA-PEFF score, using supervised machine learning algorithm (random forest analysis) to estimate high HFA-PEFF score (≥5). LA reserver strain was measured using Automated Functional Imaging (AFI) of the left atrium 3.0 version (GE Healthcare)
Statistical significant of LA reservoir strain to estimate high HFA-PEFF score (≥5)
时间窗: through study completion, an average of 1 year
Statistical significant of LA reservoir strain to estimate high HFA-PEFF score (≥5) in multiple linear regression analysis.
次要结局
未报告次要终点
研究者
Minkwan Kim, MD
Clinical assistant professor
Yonsei University