Skip to main content
MedPathMedPath Home
Clinical Trials/NCT03478618
NCT03478618
Unknown
Early Phase 1

Comparison of Two Different Protocols of Fluid Therapy in Severe Preeclamptic Patients Under Spinal Anesthesia : Hemodynamic and Kidney Function Outcome

Assiut University0 sites60 target enrollmentMarch 2018
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsHypotension Drug-Induced
InterventionsLactated Ringer
DrugsLactated Ringer

Overview

Phase
Early Phase 1
Intervention
Lactated Ringer
Conditions
Hypotension Drug-Induced
Sponsor
Assiut University
Enrollment
60
Primary Endpoint
incidence of hypotension
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSimilar Trials

Overview

Brief Summary

To compare the effect of two different protocol of fluid therapy in sever preeclamptic patients under spinal anesthesia : Hemodynamic and kidney function .

Registry
clinicaltrials.gov
Start Date
March 2018
End Date
April 2019
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Bola Fawzi Mekhail Sedrak

principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • •more than 36 weeks gestation
  • •singleton pregnant women planned for elective caesarian section

Exclusion Criteria

  • •patient refusal.
  • •psychiatric disorders.
  • •parturient \<36 weeks gestation, twins, abnormal cardiotocography (CTG) tracing.
  • •absolute contraindications for spinal anesthesia (patients refusal, raised intracranial pressure, hypovolemic states, abnormal coagulopathy).

Arms & Interventions

Group R

30 patients will receive 15ml/kg/h lactated Ringer (LR) intraoperative.

Intervention: Lactated Ringer

Group L

30 patients will receive 30ml/kg/h lactated Ringer (LR) intraoperative.

Intervention: Lactated Ringer

Outcomes

Primary Outcomes

incidence of hypotension

Time Frame: 1 hour

decrease in systolic blood pressure more than 20% of base line

Similar Trials

Unknown
Not Applicable
The Influence of Different Fluid Therapy Measures on the Postoperative Outcome in Fast Track of Colon Cancer.（FTSlapCC)Colon Carcinoma
NCT02991092Quan Wang150
Completed
Not Applicable
Fluid therapy in patients with mild diastolic dysfunction and severe systolic dysfunctioheart failure.Other forms of heart diseaseI30-I52
IRCT20200620047849N1Qazvin University of Medical Sciences130
Recruiting
Not Applicable
Comparison of fluid therapy methods in patients with sepsis: A clinical trial in the intensive care unit of Al-Zahra HospitalSepsis.Other sepsis
IRCT20240804062637N1Esfahan University of Medical Sciences60
Completed
Not Applicable
Effect of Fluid Challenge on GlycocalyxAnesthesiaEndothelial DysfunctionSepsisSeptic ShockSurgery
NCT03891342University Hospital Hradec Kralove120
Completed
Not Applicable
Intraoperative Different Fluid Therapy ProtocolsIntraoperative Fluid Management
NCT06188299Ankara City Hospital Bilkent60