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临床试验/ACTRN12618001032246
ACTRN12618001032246进行中(未招募)未知

Impulse oscillometry for the diagnosis of bronchiolitis obliterans syndrome

Dr Thomas Crowhurst0 个研究点目标入组 121 人开始时间: 2018年6月20日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
发起方
入组人数
121

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • Bilateral Lung transplant recipient
  • - 18 years old or more
  • - Allogeneic haematopoietic stem cell transplant recipient
  • - 18 years old or more

排除标准

  • In lung transplant recipients, allograft dysfunction from causes other than BOS or RAS, including:
  • - BOS / RAS overlap
  • - Active non-BOS alloinflammatory processes (e.g. acute cellular rejection, lymphocytic bronchiolitis and antibody-mediated rejection)
  • - Active allograft infection
  • - Mechanical impediment:
  • - Known upper / large airway obstructive pathology (e.g. anastomotic stricture or stricture to level of segmental bronchus)
  • - Pleural complications such as pneumothorax, infection or pleural effusion
  • - Neuromuscular deficits (e.g. diaphragmatic paralysis)
  • - Uncontrolled cardiac failure of any cause
  • - Recurrent of primary disease in allograft
  • In allogeneic haematopoietic stem cell transplant recipients, lung dysfunction from causes other than bronchiolitis obliterans including:
  • - Active pulmonary infection
  • - Mechanical impediment:
  • - Known upper / large airway obstructive pathology
  • - Pleural complications such as pneumothorax, infection or pleural effusion
  • - Neuromuscular deficits (e.g. diaphragmatic paralysis)
  • - Uncontrolled cardiac failure of any cause
  • - Pre-existing lung disease that is more than mild in severity (either obstructive or restrictive)

研究者

发起方
Dr Thomas Crowhurst

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