Acute Medium Chain Triglycerides (MCT) Intake in Young and Older Participants
- Conditions
- Ketonemia
- Registration Number
- NCT03830268
- Lead Sponsor
- Université de Sherbrooke
- Brief Summary
Compare plasma metabolites following different conditions paired with a dietary MCT beverage over an 8-hour metabolic day protocol in young and older participants.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- 10 health young (20-40 y old) and 10 health older (> 60 y old) participants
- Men and women
- smoking
- diabetes (fasting glucose >7.0 mmol/l and glycated hemoglobin >6.9%)
- strenuous aerobic exercise more than three times a week
- untreated hypertension, dyslipidemia, and abnormal renal, liver, heart or thyroid function
- under medication known to affect triglycerides and carbohydrates metabolism (i.e. diuretics, beta-blockers, steroids, insulin sensitizing)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Concentration of plasma ketones (acetoacetate and B-hydroxybutyrate) 8 hours To compare acute ketonemia following different conditions paired with a dietary MCT beverage over an 8-hour metabolic day protocol.
- Secondary Outcome Measures
Name Time Method Concentration of plasma glucose 8 hours To compare acute glucose following different conditions paired with a dietary MCT beverage over an 8-hour metabolic day protocol.
Concentration of plasma insulin 8 hours To compare acute insulin following different conditions paired with a dietary MCT beverage over an 8-hour metabolic day protocol.
Concentration of plasma free fatty acids 8 hours To compare acute free fatty acids following different conditions paired with a dietary MCT beverage over an 8-hour metabolic day protocol.
Trial Locations
- Locations (1)
Rearsh Centre on Aging
🇨🇦Sherbrooke, Quebec, Canada
Rearsh Centre on Aging🇨🇦Sherbrooke, Quebec, Canada