Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- changes in scores of the Sunnybrook grading system.
研究概览
简要总结
Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies.
Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •unilateral acute facial palsy of no identifiable cause
排除标准
- •Recurrent facial Bell's palsy
- •Pregnancy
- •Severe hypertension,
- •Renal or hepatic disease,
- •Gastric or duodenal ulcer
- •presence of acute otitis media or ipsilateral chronic otitis
- •Recent head injury,
- •psychiatric disease
- •If there is any contraindications for corticosteroids
研究组 & 干预措施
Prednisolone
干预措施: Prednisolone (Drug)
Cerebrolysin
干预措施: Cerebrolysin (Drug)
Prednisolone and Cerebrolysin
干预措施: Prednisolone (Drug)
Prednisolone and Cerebrolysin
干预措施: Cerebrolysin (Drug)
结局指标
主要结局
changes in scores of the Sunnybrook grading system.
时间窗: at baseline, after 1 week, after 3 week
change in scores of the house Brackman grading system HB
时间窗: at baseline, after 1 week, after 3 week
次要结局
未报告次要终点
研究者
engy wahsh
LECTURER OF CLINICAL PHARMACY
October 6 University