Diagnostic efficacy and effectiveness of primary whole-body computed tomography (Pan-CT) in severe and multiple trauma

Completed

Conditions: Blunt and penetrating multiple trauma
Injury, Occupational Diseases, Poisoning

Registration Number: ISRCTN41462125

Lead Sponsor: nfallkrankenhaus Berlin Trauma Centre, Centre for Clinical Research (Germany)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 700

Inclusion Criteria

PATRES-1: Hospital charts and Radiology Information System/Picture Archiving and Communication System (RIS/PACS) data from consecutive male and female patients (no age limits) who i) had been admitted to the emergency department of a metropolitan trauma centre between 01/2008 and 06/2009 and ii) were referred to Pan-CT because of suspected multiple trauma by the physician on charge

PATRES-2: Trauma leaders caring for consecutive male and female patients (no age limits) who are admitted to the emergency department of a metropolitan trauma centre and are referred to Pan-CT because of suspected multiple trauma

Exclusion Criteria

Does not meet inclusion criteria

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PATRES-1: Accuracy of Pan-CT (i.e. sensitivity, specificity, area under the ROC curve) for diagnosing i) multiple trauma, ii) individual injuries. A synopsis of all diagnoses obtained during the hospital stay (e.g. CT-scans, clinical, intra-operative, and autopsy findings) will serve as the reference standard. All images will be re-read by experienced trauma radiologists, and hospital charts will independently be evaluated by trauma surgeons. <br>PATRES-2: <br>1. Shift in the pre-test probability of the prevalence and severity of injuries as judged by trauma surgeons prior to and after Pan-CT<br>2. Related changes in clinical decision making (e.g., emergency surgery, transfer to intensive care unit [ICU])

Secondary Outcome Measures

Name	Time	Method
PATRES-1: <br>1. Rate of unnecessary CT-scans<br>2. Discrepancy between first and second readings <br><br>PATRES-2: Perceived value and effectiveness of CT-scans by trauma leaders (immediately after availability of CT-scans [i.e. at the trauma bay])