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Benefit of platanus and Rosemary extract on treatment of resistant asthma

Phase 2
Conditions
Asthma.
Asthma, unspecified
Registration Number
IRCT201107312695N2
Lead Sponsor
Vice chancellor for research, Islamic Azad University- Mashhad Branch
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

1- Resistant asthma to Inhaled corticosteroid, long acting beta 2 agonist, antileukotrien and theophyllin Exclusion criteria: 1- Respiratory infection 2- Fair Treatment with controller drugs 3- Not cooperative with project 4- congestive heart failure 5- Gastroesophageal reflux 6- Rhinosinusitis, 7- pregnancy 8- smoking 9- non asthmatic other lung disease and non pulmonary disease

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
FEV1. Timepoint: before treatment and one month after treatment. Method of measurement: spirometry superspiro, Micromedical company, England.;Exhaled Nitric oxide (FENO). Timepoint: before treatment and one month after treatment. Method of measurement: Chemiluminescence instrument, No Breath, Bedfont company, England.;ACT Questionnaire. Timepoint: before treatment and one month after treatment. Method of measurement: Validated Asthma control test Questionnaire.
Secondary Outcome Measures
NameTimeMethod
IL-17. Timepoint: Before treatment and One month after treatment. Method of measurement: ELIZA- Qiagen company Tehran Iran.;INF- Gamma. Timepoint: Before treatment and One month after treatment. Method of measurement: ELIZA- Qiagen company Tehran Iran.
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