Greater Occipital and Supraorbital Nerve Blockade For The Preventive Treatment of Migraine
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Migraine Disorders
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
- Enrollment
- 103
- Primary Endpoint
- Change of Frequency of Headache
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The investigators aimed to evaluate the efficacy of greater occipital nerve and supraorbital nerve blockade with local anesthetics for the preventive treatment of migraine without aura.
Detailed Description
A mixture of 1 ml 2% lidocaine and 0.9% 1 ml saline was injected bilaterally to GON and SON in the blockade patients. Placebo patients received 2 ml 0.9% saline in the same way. Patients were blinded to kind of injection.
Investigators
Cem Bölük
Medical Doctor
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •Lack of benefits 1 year from preventive treatment or intolerance to their treatments.
- •18 ≥ years old
- •Migraine without aura for more than 1 year, minimum of two or more migraine attacks per month.
Exclusion Criteria
- •Patients with any chronic illness, medication overuse headache, a history of cranial and cervical surgery
- •Allergies to local anesthetics
- •Hemorrhagic diathesis
- •Alcohol or drug abuse
Outcomes
Primary Outcomes
Change of Frequency of Headache
Time Frame: Patients were followed up from baseline to 2 months after first injection.
Number of headache days in a month. Scores from both months were averaged. Minimum=0 Maximum=30. Lower scores mean a better outcome.
Change of Severity of Headache
Time Frame: Patients were followed up for 2 months from baseline after first injection.
Mean visual analog scale (VAS) scores. Scores from both months were avareged. Minimum=0 Maximum=10. Lower scores mean a better outcome