Analgesic Efficacy of Ultrasound-guided Greater Occipital Nerve Block in Patients of Chronic Migraine
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Analgesic efficacy
研究概览
简要总结
The study was carried to determine the analgesic efficacy of greater occipital nerve block in patients of migraine. It was a randomised controlled which took place from april 2022 - october 2022. Fifty patients suffering from migraine were included in the study. Patients in Group G were given greater occipital nerve block (GONB) with lignocaine and dexamethasone under ultrasound guidance while those in Group S were given saline 0.9% as placebo. Pain score using Numeric Rating Scale and number of headache days was assessed at four,eight and twelve weeks after the procedure as a primary outcome. Total headache days were recorded as a secondary outcome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients between 18 to 60 years
- •diagnosed case of migraine
排除标准
- •Patients with known allergies to local anaesthetics
- •pregnancy
- •history of cranial or cervical surgery
- •head injury
- •headaches secondary to medication overuse
- •patients with uncontrolled systemic disease like blood pressure, diabetes mellitus
- •hypo or hyperthyroidism
- •patient who had already received GONB or botulinum toxin type A therapy within last 6 months
- •major psychiatric disorder
- •history of chronic pain syndromes
研究组 & 干预措施
Group G
Greater occipital nerve block (GONB) under ultrasound guidance with lidocaine and dexamethasone on the side of headache
干预措施: Greater Occipital Nerve Block with dexamethasone and lidocaine (Drug)
Group G
Greater occipital nerve block (GONB) under ultrasound guidance with lidocaine and dexamethasone on the side of headache
干预措施: Greater Occipital Nerve Block with 0.9% saline (Drug)
Group S
Greater occipital nerve block (GONB) under ultrasound guidance on the side of headache with 0.9% Saline (Placebo)
干预措施: Greater Occipital Nerve Block with dexamethasone and lidocaine (Drug)
Group S
Greater occipital nerve block (GONB) under ultrasound guidance on the side of headache with 0.9% Saline (Placebo)
干预措施: Greater Occipital Nerve Block with 0.9% saline (Drug)
结局指标
主要结局
Analgesic efficacy
时间窗: 12 weeks
Change in Pain score assessed on Numeric Rating Scale (NRS) which ranges from 0 to 10. 0 is no pain and 10 is maximum pain.
次要结局
- Headache days(12 weeks)
研究者
Moazzam Ali
Doctor, Head Of Department
Pain Medicine Department