Analgesic Efficacy of Ultrasound-guided Greater Occipital Nerve Block in Patients of Chronic Migraine
Overview
- Phase
- Phase 4
- Intervention
- Greater Occipital Nerve Block with dexamethasone and lidocaine
- Conditions
- Chronic Migraine
- Sponsor
- Pain Medicine Department
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Analgesic efficacy
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The study was carried to determine the analgesic efficacy of greater occipital nerve block in patients of migraine. It was a randomised controlled which took place from april 2022 - october 2022. Fifty patients suffering from migraine were included in the study. Patients in Group G were given greater occipital nerve block (GONB) with lignocaine and dexamethasone under ultrasound guidance while those in Group S were given saline 0.9% as placebo. Pain score using Numeric Rating Scale and number of headache days was assessed at four,eight and twelve weeks after the procedure as a primary outcome. Total headache days were recorded as a secondary outcome.
Investigators
Moazzam Ali
Doctor, Head Of Department
Pain Medicine Department
Eligibility Criteria
Inclusion Criteria
- •Patients between 18 to 60 years
- •diagnosed case of migraine
Exclusion Criteria
- •Patients with known allergies to local anaesthetics
- •pregnancy
- •history of cranial or cervical surgery
- •head injury
- •headaches secondary to medication overuse
- •patients with uncontrolled systemic disease like blood pressure, diabetes mellitus
- •hypo or hyperthyroidism
- •patient who had already received GONB or botulinum toxin type A therapy within last 6 months
- •major psychiatric disorder
- •history of chronic pain syndromes
Arms & Interventions
Group G
Greater occipital nerve block (GONB) under ultrasound guidance with lidocaine and dexamethasone on the side of headache
Intervention: Greater Occipital Nerve Block with dexamethasone and lidocaine
Group G
Greater occipital nerve block (GONB) under ultrasound guidance with lidocaine and dexamethasone on the side of headache
Intervention: Greater Occipital Nerve Block with 0.9% saline
Group S
Greater occipital nerve block (GONB) under ultrasound guidance on the side of headache with 0.9% Saline (Placebo)
Intervention: Greater Occipital Nerve Block with dexamethasone and lidocaine
Group S
Greater occipital nerve block (GONB) under ultrasound guidance on the side of headache with 0.9% Saline (Placebo)
Intervention: Greater Occipital Nerve Block with 0.9% saline
Outcomes
Primary Outcomes
Analgesic efficacy
Time Frame: 12 weeks
Change in Pain score assessed on Numeric Rating Scale (NRS) which ranges from 0 to 10. 0 is no pain and 10 is maximum pain.
Secondary Outcomes
- Headache days(12 weeks)