Comparative study between intravenous Clonidine and intravenous Lignocaine in the attenuation of pressor responses to laryngoscopy and endotracheal intubation.

Dr Shahbaz Haroon1 个研究点分布在 1 个国家目标入组 70 人开始时间: 2021年10月30日最近更新: 2021年2月10日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 70
试验地点: 1
主要终点: To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with intravenous clonidine

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

It is a randomized, prospective, comparative, double blinded, observational study where in intravenous lignocaine and intravenous clonidine are compared for the attenuation of hemodynamic pressor responses during laryngoscopy and endotracheal intubation before any surgical procedures in the operation theatre.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•Age between 18-60 yr of either sex.
•ASA grade I and grade II.
•Patients posted for elective surgeries under general anesthesia requiring intubation.
•Hemodynamically stable patients having all routine investigations within normal limits.
•Patients who give written informed consent and are willing to be part of the study.

排除标准

•Patients refusal.
•Patients with ASA physical status III and more.
•Patients with any pre-existing cardiovascular disease.
•Patients with h/o allergy to test drugs.
•Patients posted for emergency surgeries.
•Patients with difficult airway.
•Patients with neurological disorders and muscle diseases.

结局指标

主要结局

To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with intravenous clonidine

时间窗: PRE INTUBATION, SCOPY 0 MINS, EVERY 5 MINUTES, UPTO 2 HOURS INTRA-OP, POST OP VAS, SEDATION

次要结局

To study the side effects of Clonidine and Lignocaine, if any and Ramsay sedation scale(Ramsay sedation scale: immediately, 1 hour, 6 hour and 12 hour after surgery)

研究者

发起方

Dr Shahbaz Haroon

申办方类型

Other [self]

研究点 (1)

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