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Comparison of Vascular Risk in Patients Treated for Obstructive Sleep Apnea/Hypopnea Syndrome

Completed
Conditions
Obstructive Sleep Apnea/Hypopnea Syndrome
Registration Number
NCT05491967
Lead Sponsor
Centre Hospitalier de Valence
Brief Summary

a monocentric,non interventional, prospective study to compare cardiovascular risk in patients with Obstructive Sleep Apnea/Hypopnea Syndrome treated with Continuous Positive Airway Pressure (CPAP) and Mandibular Advancement Orthosis.

Detailed Description

The first-line treatment of severe Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) is nocturnal ventilation with Continuous Positive Airway Pressure (CPAP). and The second-line treatment is the mandibular advancement orthosis (MAO)\].

CPAP is the most effective treatment to reduce the apnea-hypopnea index (AHI). However, its tolerance is sometimes difficult, causing many discontinuations.

The purpose of this review is to evaluate a vascular morbimortality criteria:

* Cardiovascular: myocardial infarction, heart failure, rhythm disorder

* Neurological: transient or non transient stroke

* ophthalmologic: anterior ischemic optic neuropathy, occlusion of the central artery or central retinal vein occlusion

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
172
Inclusion Criteria
  • Obstructive Sleep Apnea/Hypopnea Syndrome treated with With Continuous Positive Airway Pressure (CPAP) or Mandibular Advancement Orthosis
  • Age ≥ 18 years old
  • Read, write and understand the French language
Exclusion Criteria
  • Patient under guardianship, deprived of liberty, safeguard of justice
  • Refusal to participate in research

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
morbimortality vascular criteriaup to 6 months

Presence or absence of ophthalmologic event

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Ch Valence

🇫🇷

Valence, Drome, France

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