Effect of Dietary Fat on Glycemic Control in Type 1 Diabetes

Not Applicable

Completed

• Conditions: Type 1 Diabetes
• Interventions: Other: High fat meal

• Registration Number: NCT01292590
• Lead Sponsor: Joslin Diabetes Center

Brief Summary

The purpose of this study is to determine if dietary fat alters insulin requirements in type 1 diabetes.

Detailed Description

This cross-over prospective study will require a two day admission to the clinical research center. Subjects will undergo closed loop glucose control and will received a diet with controlled macronutrient content.

Study Timeline

• Study Start: 2010-09
• Study First Submitted: 2010-10-21
• Study First Submitted QC: 2011-02-08
• Study First Posted: 2011-02-09
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-25
• Last Update Posted: 2017-04-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• type 1 diabetes using insulin pump and CGM

Exclusion Criteria

• renal or hepatic failure
• cancer or lymphoma
• malabsorption or malnourishment
• hypercortisolism
• alcoholism or drug abuse
• anemia (hematocrit < 36 in females and <40 in males)
• eating disorder
• dietary restrictions
• Acetaminophen allergy
• Chronic acetaminophen use
• Glucocorticoid therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
High fat meal	High fat meal	-

Primary Outcome Measures

Name	Time	Method
Change in insulin requirements	postprandially until 8 hours

Trial Locations

Locations (1)

Beth Israel Deaconess Medical Center; 🇺🇸 Boston, Massachusetts, United States