Comparative evaluation of antibacterial efficacy of 2 percent Chlorhexidine and 6 percent Chitosan as irrigating solutions in nonvital primary teeth An invivo study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Evaluation of bacterial load before and after irrigation to assess the antibacterial efficacy of 2% Chlorhexidine and 6% Chitosan in pediatric patients
研究概览
简要总结
The randomised clinical trial aims to compare the antibacterial efficacy of 2% Chlorhexidine and 6% Chitosan as irrigating solutions in non-vital primary teeth. Children between 4 to 9 age group without any systemic disease will be enrolled. Access opening of the non-vital tooth will be done under all aseptic conditions. Pre-irrigation sample will be collected with sterile paper points and after using irrigant post-irrigation sample will be collected and transferred to sterile transport media immediately. Both the samples will be incubated on blood agar. Colonies formed will be counted to assess the bacterial load.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 4.00 Year(s) 至 9.00 Year(s)（—）
- 性别
- All
入选标准
- •Primary teeth with chronic pulpitis, chronic periapical abscess, acute exacerbation of chronic pulpitis, and chronic periapical abscess Primary molars with minimal mobility and restorable crown Minimal root resorption No sinus tract Parents/caregivers acceptance and cooperation.
排除标准
- •Teeth having furcal lesions more than 5 mm diameter or periapical lesions exceeding 10 mm diameter.
- •Children with systemic diseases and patients undergone antibiotic therapy in the past 3 months.
- •Children whose parents have refused to participate in the study.
结局指标
主要结局
Evaluation of bacterial load before and after irrigation to assess the antibacterial efficacy of 2% Chlorhexidine and 6% Chitosan in pediatric patients
时间窗: Baseline (Before Intervention): Pre-treatment microbial sampling will be collected immediately after access opening | Post-irrigation (After Intervention): Sample will be collected 30 minutes irrigation to assess the reduction in bacterial load.
次要结局
- Antibacterial efficacy of two different irrigants used(Pre-irrigation and post-irrigation)
研究者
Dr Shere Shraddha Vivekanand
NIMS University