Comparative evaluation of the Antimicrobial efficacy of 0.2 percent Chlorhexidine and Herbal mouthwash on Salivary Bacterial load: A Randomized Controlled Trial.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Assessment of salivary bacterial load and candida albicans
研究概览
简要总结
This Randomized Controlled Trial will be conducted for a period of ten days on 20 randomly selected patients having mild to moderate gingivitis allocated into two groups - 0.2% chlorhexidine mouthwash and oralife mouthwash, ten in each group. Unstimulated saliva samples will be collected before rinsing with mouthwash, immediately after rinsing with mouthwash and one hour after using mouthwash and on eleventh day after usage of mouthwash 5ml twice daily for ten days. Sample will be examined in laboratory for microbiological assessment to measure the bacterial load and candida albicans.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having mild to moderate gingivitis reporting in OPD of Faculty of Dental Sciences IMS BHU.
- •All teeth and surrounding tissues were clinically and radiographically free of any other pathologic condition.
- •Healthy individuals without any systemic diseases.
排除标准
- •Physical limitations, which might preclude the normal tooth brushing and mouth rinsing.
- •Presence of any severe intraoral infections.
- •Medically compromised patients or those who were on any long-term medication.
- •Subjects with history of taking antibiotics 1 month prior to or during the course of study.
- •Patient reporting with pain or history of pain requiring immediate treatment.
- •Subjects with fixed or removable orthodontic appliances or removable prosthesis.
结局指标
主要结局
Assessment of salivary bacterial load and candida albicans
时间窗: Assessment of salivary bacterial load and candida albicans at baseline ,immediate after rinsing with mouthwash and after 10 days of regular rinsing with mouthwash
次要结局
未报告次要终点
研究者
Dr Mahesh R Khairnar
Faculty of Dental Sciences IMS, Banaras Hindu University, Varanasi ,221005, Uttar Pradesh, India