A study to determine if a new procedure(Thromboelastography guided blood product transfusion)can help in chronic liver disease patients undergoing invasive liver related procedures.
- Conditions
- Health Condition 1: null- patients undergoing invasive liver related procedures in patients with chronic liver disease.
- Registration Number
- CTRI/2017/12/010822
- Lead Sponsor
- Department of Gastroenterology AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patient undergoing invasive liver related procedures (eg, percutaneous liver biopsy, transjugular liver biopsy, transarterial chemoembolization, hepatic vein angioplasty/stenting, transjugular intrahepatic portosystemic shunt (TIPS)
2.Age between 18-65 years
3.Willing to participate in the study
1.Patients with malignancy/disseminated intravascular coagulation (DIC)/known coagulopathic disorder (haemophilia) apart from cirrhosis.
2.History of intake of platelets inhibitors (eg, aspirin, clopidogrel) and drugs affecting coagulation cascade (eg, vitamin K anatagonists) within past 7 days
3.Pregnant women and those on oral contraceptives
4.Patients with chronic renal failure
5.History of underlying hypercoagulable/ hypocoagulable states eg. paroxysmal nocturnal hemoglobunuria(PNH), polycythemiavera etc
6.Patients receiving blood products (fresh frozen plasma and platelet prior to thromboelastography)
7.Patients with shock
8.Sepsis
9.Not willing to provide consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method