Thromboelastometry Guided Blood-Component Therapy After Cardiac Surgery: A Randomized Study

Not Applicable

• Conditions: T81.0; D68.4; Haemorrhage and haematoma complicating a procedure, not elsewhere classified; Acquired coagulation factor deficiency

• Registration Number: DRKS00017367
• Lead Sponsor: Herzzentrum Universität Leipzig

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-18
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 104

Inclusion Criteria

• indication for cardiac surgery
• patient consent signed
• elective surgery
• age over 18 years
• persistent postoperative bleeding defined as drainage loss of 100 ml / 30 min or more than 200 ml / h after arrival at the intensive care unit

Exclusion Criteria

• patient with preoperatively known treatment-relevant coagulation disorder (haemophilia A / B, APC-resistance, factor XIII deficiency, HIT-II, etc.)
• pregnancy or breastfeeding

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary endpoints are transfusion requirements regarding red blood cells, platelets, plasma, fibrinogen or pooled factors.

Secondary Outcome Measures

Name	Time	Method
The secondary endpoints are 24-hour drainage loss, re-thoracotomy rate and cost analysis of blood and coagulation products.