Comparing Efficacy Of Perineural Versus Intravenous Dexmedetomidine as an Adjuvant to 0.5 % Levobupivacaine in ultrasound guided Supraclavicular Brachial Plexus Block in Upper Limb Surgeries in Department of Anaesthesia at SMS Hospital ,Jaipur
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- To assess and compare the difference in mean duration of analgesia in both
Study Overview
Brief Summary
In this study we plan to study and draw comparison of effect of dexmedetomidine when given near nerves versus when given intravenous.
The study will be conducted in following two groups of patients. Study will consist of 100 patients. GROUP A 50 patients will receive Perineural 25ml 0.5% Levobupivacaine plus 1mcg/kg Dexmedetomidine diluted in 2ml NS for ultrasound guided supraclavicular brachial plexus block. along with IV 50 ml Normal saline administered as infusion over 10 minutes. GROUP B 50 patients will receive Perineural: 25ml 0.5% Levobupivacaine plus 2ml NS for ultrasound guided supraclavicular brachial plexus block IV 1 μg/kg-1 dexmedetomidine in 50 mL of normal saline administered as infusion over 10 minutes
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients who Will give informed written consent Either sex American Society of Anesthesiologists Physical Status (ASA-PS) Classes I and II Posted for upper limb surgeries Body weight :– 40-70 kg.
Exclusion Criteria
- •Patients having severe systemic illness and bleeding disorders, Pregnant women Patients allergic to study drugs Patients having peripheral neuropathy or motor neuron disorders Patients having pathology at infection site Disability limiting the preferences of block.
Outcomes
Primary Outcomes
To assess and compare the difference in mean duration of analgesia in both
Time Frame: 0,5,10,15,20,25,30,45,60,75,90 minutes
the groups.
Time Frame: 0,5,10,15,20,25,30,45,60,75,90 minutes
Secondary Outcomes
- Onset of sensory block (minutes)(Onset of motor block (minutes))
Investigators
Dr Poonam Kalra
Sawai Man Singh Medical College