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临床试验/CTRI/2024/01/061745
CTRI/2024/01/061745尚未招募3 期

Comparing Efficacy Of Perineural Versus Intravenous Dexmedetomidine as an Adjuvant to 0.5 % Levobupivacaine in ultrasound guided Supraclavicular Brachial Plexus Block in Upper Limb Surgeries in Department of Anaesthesia at SMS Hospital ,Jaipur

Sawai Man Singh Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年1月26日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
To assess and compare the difference in mean duration of analgesia in both

研究概览

简要总结

In this study we plan to study and draw comparison of effect of dexmedetomidine when given near nerves versus when given intravenous.

The study will be conducted in following two groups of patients. Study will consist of 100 patients. GROUP A  50 patients will receive Perineural 25ml 0.5% Levobupivacaine plus 1mcg/kg Dexmedetomidine diluted in 2ml NS for ultrasound guided supraclavicular brachial plexus block. along with IV 50 ml Normal saline administered as infusion over 10 minutes.  GROUP B 50 patients will receive  Perineural: 25ml 0.5% Levobupivacaine plus 2ml NS for ultrasound guided supraclavicular brachial plexus block  IV 1 μg/kg-1 dexmedetomidine in 50 mL of normal saline administered as infusion over 10 minutes

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients who Will give informed written consent Either sex American Society of Anesthesiologists Physical Status (ASA-PS) Classes I and II Posted for upper limb surgeries Body weight :– 40-70 kg.

排除标准

  • Patients having severe systemic illness and bleeding disorders, Pregnant women Patients allergic to study drugs Patients having peripheral neuropathy or motor neuron disorders Patients having pathology at infection site Disability limiting the preferences of block.

结局指标

主要结局

To assess and compare the difference in mean duration of analgesia in both

时间窗: 0,5,10,15,20,25,30,45,60,75,90 minutes

the groups.

时间窗: 0,5,10,15,20,25,30,45,60,75,90 minutes

次要结局

  • Onset of sensory block (minutes)(Onset of motor block (minutes))

研究者

发起方
Sawai Man Singh Medical College and Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Poonam Kalra

Sawai Man Singh Medical College

研究点 (1)

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