Comparing Efficacy Of Perineural Versus Intravenous Dexmedetomidine as an Adjuvant to 0.5 % Levobupivacaine in ultrasound guided Supraclavicular Brachial Plexus Block in Upper Limb Surgeries in Department of Anaesthesia at SMS Hospital ,Jaipur
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To assess and compare the difference in mean duration of analgesia in both
研究概览
简要总结
In this study we plan to study and draw comparison of effect of dexmedetomidine when given near nerves versus when given intravenous.
The study will be conducted in following two groups of patients. Study will consist of 100 patients. GROUP A 50 patients will receive Perineural 25ml 0.5% Levobupivacaine plus 1mcg/kg Dexmedetomidine diluted in 2ml NS for ultrasound guided supraclavicular brachial plexus block. along with IV 50 ml Normal saline administered as infusion over 10 minutes. GROUP B 50 patients will receive Perineural: 25ml 0.5% Levobupivacaine plus 2ml NS for ultrasound guided supraclavicular brachial plexus block IV 1 μg/kg-1 dexmedetomidine in 50 mL of normal saline administered as infusion over 10 minutes
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients who Will give informed written consent Either sex American Society of Anesthesiologists Physical Status (ASA-PS) Classes I and II Posted for upper limb surgeries Body weight :– 40-70 kg.
排除标准
- •Patients having severe systemic illness and bleeding disorders, Pregnant women Patients allergic to study drugs Patients having peripheral neuropathy or motor neuron disorders Patients having pathology at infection site Disability limiting the preferences of block.
结局指标
主要结局
To assess and compare the difference in mean duration of analgesia in both
时间窗: 0,5,10,15,20,25,30,45,60,75,90 minutes
the groups.
时间窗: 0,5,10,15,20,25,30,45,60,75,90 minutes
次要结局
- Onset of sensory block (minutes)(Onset of motor block (minutes))
研究者
Dr Poonam Kalra
Sawai Man Singh Medical College
