Periodontal treatment effects on serum levels of C-reactive protein, leptin, and adiponectin in Thai patient with overweight or obesity: a pilot study

Phase 1

Recruiting

• Conditions: ormal weight Overweight/obesitynon- moderate to severe periodontitismoderate to severe periodontitis; Overweight/obesity; C- reactive protein; leptin; adiponectin

• Registration Number: TCTR20170607003
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-07
• Study Completion: 2017-10-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

- male or female , 35 years of age or older
-BMI ≥ 23 kg/m2 and WC ≥ 85 cm in men, WC ≥ 80 cm in women
or BMI < 23 kg/m2 and WC < 85 cm in men, WC < 80 cm in women
-at least 9 teeth (excluding third molars and teeth with indicated for extraction)
-diagnosis to moderate to severe periodontitis if CAL ≥ 3 mm, ≥ 30% sites and BOP ≥ 10%
or diagnosis to not moderate to severe periodontitis if CAL ≤ 2 mm
and BOP ≥ 10%
-patients who comply and participate in the study

Exclusion Criteria

- presence of systemic disease of systemic condition that could affect the progression of periodontitis and treatment or systemic disease requiring prophylactic antibiotic coverage before dental treatment
- diabetes mellitus
- hypertention
- cardiovascular disease

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
serum levels of C-reactive protein, leptin, and adiponectin baseline, 3 month and 6 month after non- surginal periodontal treatment blood examination

Secondary Outcome Measures

Name	Time	Method
none none none