Investigating bedtime procrastination and circadian phase in patients with delayed sleep phase disorder

Completed

Conditions: disorder of the biological clock
sleep disorder
10040998

Registration Number: NL-OMON43738

Lead Sponsor: Philips Research

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 168

Inclusion Criteria

DSPD patients:
-diagnosed with DSPD accruing to the International Classification of Sleep Disorders, ICSD
-age between 18 and 55 years
-score between 6-15 on the Horne Ostberg Chronotype Questionnaire;healthy controls:
-score between 16-32 on the Horne Ostberg Chronotype Questionnaire
-age between 18 and 55 years
-no self-reported (chronic) sleep complaints

Exclusion Criteria

• unable to speak and read Dutch.
• vulnerable groups, such as people with psychotic illness, severe intellectual disability, or cognitive dysfunction.
• Shift work or transmeridian flights within 1 month prior to the study
• Presence of other dominant sleep disturbances as apparent from polysomnography examination

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary objective of the study is to investigate whether patients with DSPD<br /><br>suffer more from bedtime procrastination as compared to age- and sex-matched<br /><br>controls.<br /><br>A1) A comparison of DSPD-patients* average score on the Bedtime Procrastination<br /><br>Scale (BPS) compared to age- and sex-matched healthy controls. A2) To evaluate<br /><br>the correlation between DLMO (Dim Light Melatonin Onset) and the score on the<br /><br>BPS in DSPD patients, to explore the relation between having a late circadian<br /><br>rhythm and the degree of bedtime procrastination.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>B1) To investigate whether DSPD patients show increased reward dependence as<br /><br>compared to controls.<br /><br>B2) To evaluate whether subtypes of DSPD patients can be identified with<br /><br>respect to reward dependence, lifestyle behaviour and occurrence of<br /><br>co-morbidities.<br /><br>B3) To provide insight into needs, wishes and pitfalls of DSPD patients with<br /><br>respect to chronotherapy.<br /><br>B4) To validate the phase estimation algorithm developed at Philips Research.</p><br>