Neuropsychological Evaluation of Psychiatric and Neurological Patients

Completed

• Conditions: Mood Disorder; Head Injury; Schizophrenia; Seizures; Anxiety Disorder

• Registration Number: NCT00001192
• Lead Sponsor: National Institute of Mental Health (NIMH)

Brief Summary

This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.

The goals of this research study are to;

1. Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.

2. Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.

Detailed Description

Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generalized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.

Study Timeline

• Study Start: 1983-10-18
• Study First Submitted: 1999-11-03
• Study First Submitted QC: 1999-11-03
• Study First Posted: 1999-11-04
• Status Verified: 2006-12-20
• Study Completion: 2006-12-20
• Last Update Submitted: 2017-06-30
• Last Update Posted: 2017-07-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4300

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (7)

Childrens National Medical Center; 🇺🇸 Washington, D.C., District of Columbia, United States

National Institutes of Health Clinical Center, 9000 Rockville Pike; 🇺🇸 Bethesda, Maryland, United States

Henry Ford Health Systems; 🇺🇸 Detroit, Michigan, United States

Mt. Sinai Medical Center; 🇺🇸 New York, New York, United States

Columbia University; 🇺🇸 New York, New York, United States

Mosco Research Institute of Psychiatry; 🇷🇺 Moscow, Russian Federation

Genethon; 🇫🇷 Every Cedex, France