Dynamic chest radiography in patients with asthma, COPD, COVID-19 and ILD: a pilot study

Royal Liverpool University Hospital0 个研究点目标入组 58 人开始时间: 2023年12月13日最近更新: 2024年5月27日

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•1. Undergoing PFTs in the next 6 months for clinical reasons
•2. Asthma group:
•2.1. A clinical history in keeping with asthma
•2.2. Physiological evidence of asthma (defined as post bronchodilator reversibility, variable FEV1
•over time or a previous positive bronchial challenge test)
•3. COPD group:
•3.1. A clinical history in keeping with COPD
•3.2. Physiological evidence of COPD (FEV1/FVC ratio of <0.7)
•4. ILD group:
•4.1. A clinical history in keeping with ILD
•4.2. HRCT findings in keeping with ILD
•5. Post-COVID-19 group:
•5.1. Serologically confirmed COVID-19 infection
•5.2. Chest X-ray or CT findings in keeping with COVID-19
•5.3. At least 12 weeks post-recovery from acute COVID-19
•6. Fluent spoken English - to ensure a comprehensive understanding of the research project and their proposed involvement
•7. Able to achieve positioning for a PA and lateral chest X-ray for a 30-second period

•1. Unable to provide informed consent
•2. Significant other respiratory co-morbidities as judged by study doctor
•3. Recent/ongoing exacerbation of airways disease or interstitial lung disease within the last 4 weeks (from the recruitment date).
•4. Women of child bearing age; a positive pregnancy test or refusal of pregnancy test (a negative pregnancy test on the day of DCR is a requirement).
•5. Significant research-related radiation exposure in the last 12 months prior to consent (from participation in previous studies involving radiation exposure, with a research dose constraint of 0.4 mSv).

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