Intraoperative Sedatives and Postoperative Pain
- Registration Number
- NCT02784626
- Lead Sponsor
- Seoul National University Bundang Hospital
- Brief Summary
In this study, based on the hypothesis that dexmedetomidine administered intraoperatively for sedation can reduce postoperative pain than that of propofol, the investigators examined the ability of dexmedetomidine to reduce postoperative pain in in patients undergoing the total knee arthroplasty.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
- Patients undergoing total knee arthroplasty
- Age: 20 - 80 yrs
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Exclusion Criteria
- ASA classification ≥ 3
- Patient who do not want sedation during the surgery
- Patient who wants general anesthesia
- Cardiovascular disease
- Liver dysfunction
- Renal dysfunction
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Dexmedetomidine Dexmedetomidine Patients who received dexmedetomidine during the operation Propofol Propofol Patients who received propofol during the operation
- Primary Outcome Measures
Name Time Method Visual analogue scale Postoperative 24 hours Postoperative pain score at postoperative 24 hours
- Secondary Outcome Measures
Name Time Method Rescue analgesics Postoperative 48 hours Amount of rescue analgesics administered during 48 hours postoperatively
Visual analogue scale Postoperative 48 hours Postoperative pain score at postoperative 48 hours
Trial Locations
- Locations (1)
Seoul National University Bundang Hospital
🇰🇷Seongnam-si, Gyeonggi-do, Korea, Republic of