Role of exercise and diet in disuse atrophy in hip surgery patients

Not Applicable

Completed

• Conditions: Sarcopenia; Musculoskeletal Diseases

• Registration Number: ISRCTN32820033
• Lead Sponsor: Barts and the London School of Medicine (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-03-17
• Last Update Posted: 8 May 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Elderly patients (60+ years), males and females, awaiting elective total hip arthroplasty but otherwise in relatively good health
2. Participants must have a good understanding of English to understand verbal explanations and written information given in English
3. Participants must be able to give fully informed consent

Exclusion Criteria

All participants will be screened by a physician and will be excluded from the study if they suffer from or have ever suffered from:
1. Previous stroke
2. Uncontrolled cardiovascular disease
3. Motor neurone disease
4. Parkinson's disease
5. Medically diagnosed osteoporosis
6. Type II diabetes
7. Hypertension or myocardial infarction within the previous 2 years
8. Acute febrile or systemic disease within the past 2 years
9. Currently taking beta blockers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Muscle thickness and architecture, measured by ultrasound<br>2. Muscle strength, measured by dynamometer<br>These outcomes will be assessed at baseline (10 weeks prior to surgery), immediately prior to surgery, and at 1 and 3 months post surgery.