Identification of Visual Dependence in PPPD Patients With the Aid of Virtual Reality.

Not Applicable

Recruiting

• Conditions: PPPD
• Interventions: Device: Optokinetic stimulation through Virtual Reality

• Registration Number: NCT06017908
• Lead Sponsor: Universitair Ziekenhuis Brussel

Brief Summary

The aim of this study is to evaluate whether increased visual dependence can be identified with the help of Virtual Reality (VR). Increased visual dependence is a general term for patients with increased dependence on vision in maintaining their balance. Patients suffering from persistent postural perceptual vertigo (PPPD) often suffer from increased visual dependence. This in turn leads to complaints such as visual vertigo, agoraphobia and fear of falling. Visual dependence is normally measured using the optokinetic after nystagmus (OKAN) and the rod and disc test (RDT). In this study, these two tests are performed with the aid of Virtual Reality.

Detailed Description

The aim of this study is to evaluate whether increased visual dependence can be identified with the help of Virtual Reality (VR). Visual dependence is normally measured using the optokinetic after nystagmus (OKAN) and the rod and disc test (RDT). In this study, these two tests are performed with the aid of Virtual Reality. The OKAN is measured by eye tracking, a key item already used daily in instruments such as video nystagmography (VNG) and video head impulse test (vHIT). Another test representative of visual dependence is the Rod and Disc test (RDT). In the RDT, patients are asked to complete a visual task so that researchers gain more knowledge about visual dependence. Until now, these tests have been performed using a large set-up and many different materials. Moreover, the exact underlying mechanism of visual dependence in PPPD patients is still unknown. The aim of this study is to investigate whether Virtual Reality can be a useful tool when performing the OKAN and RDT. In this way, a better understanding of visual dependence is sought. This study aims to determine the normative values for the OKAN and RDT performed with the aid of Virtual Reality. Therefore, a healthy group of individuals will be compared with PPPD patients as they suffer from visual dependence. To evaluate the effectiveness of the OKAN and RDT via VR, the results will be compared with the scores of the visual vertigo analogue scale (VVAS), a questionnaire to assess visual dependence.

Study Timeline

• Status Verified: 2023-03
• Study First Submitted: 2023-03-15
• Study First Submitted QC: 2023-08-24
• Study First Posted: 2023-08-30
• Last Update Submitted: 2024-01-29
• Last Update Posted: 2024-01-31
• Study Start: 2024-02-01
• Primary Completion: 2024-04-30
• Study Completion: 2024-07-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• All patients with chronic vertigo (>3 months)

Exclusion Criteria

• Minors
• Patients with a history of epilepsy.
• Patients with an alcohol use disorder

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
PPPD patients	Optokinetic stimulation through Virtual Reality	Virtual Reality will be used to execute the RDT and OKAN in PPPD patients.
Healthy patients	Optokinetic stimulation through Virtual Reality	Virtual Reality will be used to execute the RDT and OKAN in healthy PPPD patients.

Primary Outcome Measures

Name	Time	Method
Device feasibility	1 year	Time constant and velocity of eye movements

Trial Locations

Locations (1)

Universitair Ziekenhuis Brussel; 🇧🇪 Jette, Brussels, Belgium