Block and Erector Comparative Study Between Costotransverse Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Thoracotomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 主要终点
- study aims to compare the analgesic efficacy of CTB and ESPB for post-operative analgesia in patients undergoing thoracotomy.
研究概览
简要总结
A thoracotomy requires a very painful incision, involving multiple muscle layers, rib resection and continuous motion as the patient breathes. Treatment of acute post thoracotomy pain is particularly important not only to keep the patient comfortable but also to minimize pulmonary complications
Though epidural analgesia was once considered as the gold standard for post-thoracotomy pain management, it is not recommended for pain control after thoracotomy surgery because it is associated with high potential risks of dural puncture, nerve lesions, epidural hematoma and hypotension(4). Thoracic paravertebral block (TPVB) and intercostal nerve block are well described and recognized techniques for postoperative analgesia following thoracic surgeries, such as thoracotomy and mastectomy
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Age from 18 to 75 years old.
- •Both sexes.
- •American Society of Anesthesiologists (ASA) physical status I-II-III.
- •Patient undergoing unilateral thoracotomy surgery.
排除标准
- •• BMI more than 30 kg/m
- •Patients who are taking analgesics for chronic illness or have a history of substance abuse.
- •Patients who are unable to describe their postoperative pain (e.g., language barrier or neuropsychiatric disorder).
- •Patients with a history of coagulopathy.
- •Severe heart diseases.
- •Hepatic or renal insufficiency.
- •Infection at the site of infiltration
研究组 & 干预措施
Group CTB
n=30): patients included in this group will receive unilateral US-guided CTB after general anesthesia. The CTB will be performed by using 20 ml bupivacaine 0.25%
干预措施: Bupivacaine 0.25% Injectable Solution (Drug)
Group ESPB
patients included in this group will receive unilateral US-guided ESPB after general anesthesia. The ESB will be performed by using 20 ml bupivacaine 0.25%
干预措施: Bupivacaine 0.25% Injectable Solution (Drug)
结局指标
主要结局
study aims to compare the analgesic efficacy of CTB and ESPB for post-operative analgesia in patients undergoing thoracotomy.
时间窗: 5months
study aims to compare the analgesic efficacy of CTB and ESPB for post-operative analgesia in patients undergoing thoracotomyA standardized analgesic regimen will be prescribed in the post-operative period. All patients will receive paracetamol 1 gm every 6 h as routine analgesia. If visual analogue scale (VAS) is more than 3, intravenous morphine 3mg will be administered as rescue analgesia If visual analogue scale (VAS) is more than 5
次要结局
- The secondary outcome is the total postoperative morphine consumption, time of first analgesic,(5months)
研究者
Ahmed Mokhtar Ahmed
Resident of anesthesia department, Sohag university hospital
Sohag University