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Clinical Trials/NL-OMON31500
NL-OMON31500
Withdrawn
Not Applicable

Genetic vulnerability to stress across psychiatric diagnoses. Schizophrenia and Major Depressive Disorder - Stress and brain in psychiatry

niversitair Medisch Centrum Utrecht0 sites90 target enrollmentTBD
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Conditionspsychiatrische aandoeningenmood disorderpsychosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
psychiatrische aandoeningen
Sponsor
niversitair Medisch Centrum Utrecht
Enrollment
90
Status
Withdrawn
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Observational invasive

Investigators

Sponsor
niversitair Medisch Centrum Utrecht

Eligibility Criteria

Inclusion Criteria

  • •Subjects have to satisfy the following criteria in order to participate in the study:
  • •\- Give written informed consent
  • •\- Aged between 18\-65 years of age;Specific for schizophrenia patients:
  • •\- Do have a DSM\-IV diagnosis of Schizophrenia
  • •\- Do not chronically use medication, other than psychiatric medication
  • •\- Are not in an acute psychotic episode, but stable for at least 6 months;Specific for MDD patients:
  • •\- Do have a DSM\-IV diagnosis of Major Depressive Disorder
  • •\- Do not chronically use medication, other than psychiatric medication
  • •\- Are not in an acute depressive episode, but stable for at least 6 months
  • •\- Have had at least two depressive episodes and at least one hospital admission due to affective symptoms

Exclusion Criteria

  • •\- Ferrous objects in or around the body (e.g. braces, pacemaker, metal fragments)
  • •\- Claustrophobia
  • •\- Drug or alcohol abuse over a period of six months prior to the experiment
  • •\- History of closed\-head injury
  • •\- History of neurological illness or endocrinological dysfunction
  • •\- A pacemaker;Specific for the healthy individuals:
  • •\- A psychiatric history
  • •\- Chronic use of medication
  • •\- A first\-degree family member with a psychiatric illness

Outcomes

Primary Outcomes

Not specified

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