Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: a Relation to Periodontal Inflammaging
Not Applicable
Completed
- Conditions
- Periodontal Disease
- Registration Number
- NCT06677736
- Lead Sponsor
- Rawda Saleh Saad Alashmawy
- Brief Summary
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
- Detailed Description
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
-
Male or Female
-
Aged below 40 or above 60.
-
Have at least 16 natural teeth excluding wisdom.
-
Provide informed consent and willingness to cooperate with study protocol.
-
Periodontitis stage II patients (23):
- CAL from 3-4 mm.
- Radiographic bone loss (15% to 33%).
- No tooth loss due to periodontitis.
- Maximum probing depth ≤ 5 mm, mostly horizontal bone loss
Exclusion Criteria
- 1- Patients with any smoking habits 2- History of antibiotics in the previous three months. 3- Pregnant or lactating female. 4- Treatment with any systemic drug. 5- History of systemic disease. 6- Patients who received periodontal treatment in the last 6 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Clinical attachment loss Base line , follow up after 1 month , second follow up after 6 months Gingival index base line, follow up after 1 month, second follow up after 6 months Toll like receptor - 4 base line, follow up after 1 month, second follow up after 6 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Misr university for science and technology
🇪🇬Giza, Egypt