CWT Versus AT on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.

Not Applicable

Not yet recruiting

• Conditions: Ischemic Cardiomyopathy
• Interventions: Diagnostic Test: Circuit weight versus aerobic training

• Registration Number: NCT05674955
• Lead Sponsor: Cairo University

Brief Summary

To compare between the effect of circuit weight and aerobic training on selected cardiovascular indices and functional capacity in patients with ischemic cardiomyopathy.

Detailed Description

Ischemic cardiomyopathy (ICM) is a term that refers to the heart's decreased ability to pump blood properly due to myocardial damage brought upon by ischemia. Ischemic cardiomyopathy has a spectrum of clinical changes which eventually leads to congestive heart failure (CHF). Initially, there is a reversible loss of cardiac contractile function because of decreased oxygen supply to the heart muscle; however, when there is ischemia for a prolonged period, there is irreversible cardiac muscle damage resulting in cardiac remodeling. Remodeling is primarily achieved by myocardial fibrosis which results in decreased cardiac function, arrhythmia, and possible cardiac conduction system impairment. In ischemic cardiomyopathy, there is a significant impairment of the left ventricular systolic function, with a left ventricular ejection fraction (LVEF) less than 40% (Bhandari et al., 2021).

Study Timeline

• Study First Submitted: 2022-12-10
• Study First Submitted QC: 2022-12-29
• Study First Posted: 2023-01-09
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-20
• Last Update Posted: 2024-08-21
• Study Start: 2024-08-25
• Primary Completion: 2024-10-25
• Study Completion: 2024-10-25

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• Sixty male patients with ischemic cardiomyopathy as a result of a recent acute myocardial infarction event (≤2 months) with 40%<LVEF<50%.
• They are functionally classified as class II according to New York Heart Association (NYHA).
• Their age will be ranged from 45 to 55 years old.
• Their BMI will be ranged from 25 to 29.9 kg/m².
• They will have good mentality.

Exclusion Criteria

• Recurrent coronary heart disease.
• Severe valvular diseases.
• Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.).
• Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.).
• muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis).
• Impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control Group	Circuit weight versus aerobic training	-
Circuit weight group	Circuit weight versus aerobic training	-
Aerobic group	Circuit weight versus aerobic training	-

Primary Outcome Measures

Name	Time	Method
Ejection fraction	2 months	Will be measured by precentge

Secondary Outcome Measures

Name	Time	Method
Blood pressure	2 months	Will be measured by mmhg