Circuit Weight Versus Aerobic Training on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Ejection fraction
研究概览
简要总结
To compare between the effect of circuit weight and aerobic training on selected cardiovascular indices and functional capacity in patients with ischemic cardiomyopathy.
详细描述
Ischemic cardiomyopathy (ICM) is a term that refers to the heart's decreased ability to pump blood properly due to myocardial damage brought upon by ischemia. Ischemic cardiomyopathy has a spectrum of clinical changes which eventually leads to congestive heart failure (CHF). Initially, there is a reversible loss of cardiac contractile function because of decreased oxygen supply to the heart muscle; however, when there is ischemia for a prolonged period, there is irreversible cardiac muscle damage resulting in cardiac remodeling. Remodeling is primarily achieved by myocardial fibrosis which results in decreased cardiac function, arrhythmia, and possible cardiac conduction system impairment. In ischemic cardiomyopathy, there is a significant impairment of the left ventricular systolic function, with a left ventricular ejection fraction (LVEF) less than 40% (Bhandari et al., 2021).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 55 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Sixty male patients with ischemic cardiomyopathy as a result of a recent acute myocardial infarction event (≤2 months) with 40%<LVEF<50%.
- •They are functionally classified as class II according to New York Heart Association (NYHA).
- •Their age will be ranged from 45 to 55 years old.
- •Their BMI will be ranged from 25 to 29.9 kg/m².
- •They will have good mentality.
排除标准
- •Recurrent coronary heart disease.
- •Severe valvular diseases.
- •Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.).
- •Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.).
- •muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis).
- •Impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)
结局指标
主要结局
Ejection fraction
时间窗: 2 months
Will be measured by precentge
次要结局
- Blood pressure(2 months)
研究者
Samira Shukrey Shaffik Eshak
Domenstrator
Cairo University
