Progressive Resistance Training in Women With Knee Osteoarthritis
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Pain assessed on a 10-point numeric pain scale
研究概览
简要总结
The purpose of this study is to determine whether:
- Progressive resistance training improves pain and disability
- Progressive Resistance training improves muscular strength, ability to walk and quality of life
详细描述
Patients in experimental group participated in a 12-week progressive resistance training using a repetition maximum (RM) exercise in which patients performed 1RM with the maximum bearable weight. Once the 1RM was determined, training was divided into the following regimen: 2 series of 8 repetitions, the first with 50% and the second with 70% of 1RM.
The exercises were knee extension and flexion and hip abduction and adduction, all performed in machines. The 1RM load was reevaluated every 2 weeks.
The control group remained on a three-month waiting list for physiotherapy. Patients were assessed for pain, function, quality of life, muscle strength and six-minute walk test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age between 40-70 years old
- •Pain between 3 and 8 on a 10-point numeric pain scale
- •Radiographically confirmed knee OA
排除标准
- •Inflammatory diseases or any comorbidity that prohibit exercises, regular physical activity
- •Trip plans for the next 12 months
结局指标
主要结局
Pain assessed on a 10-point numeric pain scale
时间窗: week 0
Scale: visual analog scale
次要结局
- Disability assessed on WOMAC(week 6)
- Quality of life assessed on the SF-36(week 6)
- Six-minute walk test(week 12)