GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers

Completed

• Conditions: Sensation Disorders; Taste, Metallic; Taste Disorder, Glossopharyngeal Nerve; Taste Disorders
• Interventions: Other: swab with iron sulfate solution

• Registration Number: NCT05227157
• Lead Sponsor: Centre Hospitalier de Valence

Brief Summary

This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence.

This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste.

Detailed Description

The study consists of the application of a swab soaked in iron sulfate at a concentration of 10g/l.

each patient will rate the intensity he/she perceives (on a numerical scale from 1 to 5) at each of the 4 predefined lingual locations

Study Timeline

• Study Start: 2021-12-15
• Study First Submitted: 2022-01-26
• Study First Submitted QC: 2022-01-26
• Study First Posted: 2022-02-07
• Primary Completion: 2022-04-08
• Study Completion: 2022-05-01
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-02
• Last Update Posted: 2024-08-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age ≥ 18 years old
• Healthy volunteers
• Read, write and understand the French language
• Patient affiliated to a social security system
• Written and signed informed consent

Exclusion Criteria

• head and Neck cancer history
• olfactory and gustatory disorder
• Refusal to participate in research
• Patient under guardianship, deprived of liberty, safeguard of justice

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1: intensity of perception of metallic taste	swab with iron sulfate solution	For this study, there is only one arm: swab with iron sulfate solution at a concentration of 10g/l. Each subject complete visual scale

Primary Outcome Measures

Name	Time	Method
evaluation of the intensity of metallic taste	5 minutes	visual analogue scale (0 to 5); A score of 5 means the highest intensity of metallic taste

Trial Locations

Locations (1)

Ch Valence; 🇫🇷 Valence, Drome, France