Short-term effects of a high nitrate intake on blood pressure in treated hypertensive individuals

Completed

• Conditions: cardiovascular disease; Hypertension; Cardiovascular - Hypertension; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12613000116729
• Lead Sponsor: The University of Western Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-01-31
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

*Men and women will be aged between 50 and 70 years
*Regular use of at least one antihypertensive medication for elevated blood pressure
*Clinic/office systolic blood pressure will be >120 mmHg

Exclusion Criteria

*Use of more than 3 antihypertensive medications
*A change in antihypertensive medication within the past 1 month
*Inability to attend clinic/office visits
*Clinic/office systolic blood pressure greater than 160 mm Hg or less than 120 mm Hg; or diastolic blood pressure greater than 100 mm Hg;
*Use of antibiotics (within previous 1 months);
*current or recent (<6 months) smoking;
*body mass index < 18 or > 35 kg/m2;
*current cardiovascular or peripheral vascular disease, or diagnosed diabetes, or history of a cardiovascular event;
*a psychiatric illness, or presence of other major illnesses such as cancer;
*current or recent (within previous 6 months) significant weight loss or gain (> 6% of body weight);
*alcohol intake > 210 g per wk for women and > 280 g per wk for men;
*pregnant or lactating women;
*inability or unwillingness to consume beverages provided.

Study & Design

• Study Type: Interventional
• Study Design: Not specified