The effect of Spherical Nucleic Acids on target gene expression in full thickness biopsies taken from lesional skin of volunteers with psoriasis vulgaris.

Completed

• Conditions: psoriasis; 10003816; 10014982

• Registration Number: NL-OMON42764
• Lead Sponsor: Exicure, Inc

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 8

Inclusion Criteria

Patients with psoriasis vulgaris, moderate to severe.

Exclusion Criteria

-Volunteers undergoing light therapy or taking systemic drugs such as methotrexate or cyclosporine A.
-Volunteers using local topical corticosteroids.
-Volunteers who develop psoriasis at wound sites (Köbner phenomenon).
-Volunteers with atopic dermatitis/eczematous skin conditions.
-Pregnancy

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Psoriasis skin gene expression</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>None</p><br>