Aggressive Prostate Cancers in Elderly Patients

Completed

• Conditions: Prostatic Neoplasms

• Registration Number: NCT01347476
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Patients aged 70 years or older had a higher possibility of high risk cancer than younger patients.

Detailed Description

Patients aged 70 years or older had a higher risk of advanced prostate cancer and shorter BCR-free survival than younger ones. Definite treatment of clinically localized prostate cancer should be actively considered in well-selected healthy patients older than 70 years.

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2010-10
• Study Completion: 2010-10
• Study First Submitted: 2011-04-29
• Status Verified: 2011-05
• Study First Submitted QC: 2011-05-03
• Study First Posted: 2011-05-04
• Last Update Submitted: 2011-05-18
• Last Update Posted: 2011-05-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 1333

Inclusion Criteria

• clinically localized prostate cancer
• good health status
• follow-up period more than 12 months

Exclusion Criteria

• insufficient clinical data
• poor health status
• clinically advanced prostate cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
biochemical recurrences (BCR)	5 year-BCR	BCR was defined as two consecutive increasing PSA values of more than 0.2 ng/mL

Secondary Outcome Measures

Name	Time	Method
pathologic outcomes	postoperative 1 week	biopsy or pathologic Gleason scores, mean percent of positive cores and tumor volume percent, Extracapsular extension and seminal vesicle invasion

Trial Locations

Locations (1)

Seoul National University Boramae Hospital; 🇰🇷 Seoul, Korea, Republic of