Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
- 主要终点
- Quantitative Helicobacter Pylori IgG Assay in Serum
研究概览
简要总结
Prevalence of anti-H.pylori IgG in serum of women with unexplained infertility and comparing that with it's prevalence in fertile women.
详细描述
Unexplained infertility was diagnosed according to standard World Health Organization (WHO) criteria. All women in the study had hormonal assessment to evaluate their ovulatory cycles, thyroid function, circulating prolactin and androgen levels. The ovarian reserve was checked by measurement of serum FSH and an antral follicle count on the third day of the menstrual cycle. Screening for infertility also included transvaginal ultrasound and hysterosalpingography, to exclude possible uterine malformations or pathologies, and to assess the patency of the fallopian tubes. Male factor infertility was excluded in all couples, according to standard WHO semen analysis.
Following admission, all patients underwent complete clinical examination and detailed medical history was obtained.
A venous sample was collected to test serum for HP IgG seropositivity by enzyme linked immunoassay for HELICOBACTOR PYLORI IgG (ENZYME IMMUNOASSAY TEST KIT).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •regular cycles.
- •normal thyroid function, prolactin and androgen levels.
- •normal semen analysis of the partner.
- •normal hysterosalpingography.
- •normal transvaginal ultrasound examination.
排除标准
- •possible uterine malformations or pathologies.
- •presence of infections, including hepatitis, human immunodeficiency virus (HIV), TORCH, Chlamydia trachomatis and Mycoplasma.
- •presence of anti-sperm antibodies in serum.
- •Male factor infertility.
结局指标
主要结局
Quantitative Helicobacter Pylori IgG Assay in Serum
时间窗: 24 hours
calculation of quantitative Helicobacter pylori IgG assay in serum
次要结局
未报告次要终点
研究者
Amr Ahmed Mahmoud Riad
Lecturer of obstetrics and gynecology
Ain Shams Maternity Hospital
