Study on the association of eosinophilic esophagitis and resident microbial composition.
Not Applicable
Recruiting
- Conditions
- eosinophilic esophagitis
- Registration Number
- JPRN-UMIN000031570
- Lead Sponsor
- Shimane university school of medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Not provided
Exclusion Criteria
1) daily usage of steroids, immunosuppresive and anticancer drugs 2) 20 or fewer teeth 3) using antibiotics during use or within 1 month 4) During pregnancy, lactating, a woman who may be pregnant 5) history of allergy to esomeprazole 6) A case of a history of resection of the gastrointestinal tract except for appendectomy 7) the research director judged inappropriate as the subject of this research
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Healthy volunteers, patients with reflux esophagitis or eosinophilic esophagitis donated the fecal, saliva, periodontal pocket fluid and scraching samples of esophagus mucous. We then investigate the effect of PPIs on the bacterial communities using 16S rRNA gene sequencing method.
- Secondary Outcome Measures
Name Time Method