The association between tissue eosinophilia and the time to disease recurrence of chronic rhinosinusitis after endoscopic sinus surgery

Not Applicable

Recruiting

• Conditions: Chronic Rhinosinusitis; chronic rhinosinusitis; eosinophilic rhinosinusitis; Nasal Polyps; endoscopic sinus surgery; recurrent sinusitis; uncontrolled sinusitis

• Registration Number: TCTR20150719001
• Lead Sponsor: &#45

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07-19
• Study Completion: 2017-07-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Chronic rhinosinusitis patients according to EPOS 2012 guideline
• age 18 or older
• failed fully medication at least 3 months including antibiotics, intranasal/oral corticosteroid, nasal irrigation.

Exclusion Criteria

ofungal or dental origin causing rhinosinusitis
oMucocele
oBenign and malignant Neoplasms
oCystic fibrosis
oimmunodeficiency status
oCongenital mucociliary problems (eg. Primary ciliary dyskinesia)
oSystemic vasculitis and granulomatous disease
oCocaine abuse

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ncontrolled status of Chronic rhinosinusitis after sinus surgery from day after surgery to the maximum of 2 years Time to event of uncontrolled disease status, number of months

Secondary Outcome Measures

Name	Time	Method
outcome of treatment, risk factors of mortality 28 days clinical observation