What happens to human information processing during anesthesia: the effect of a sub-anesthetic dose of S-Ketamine

Completed

• Conditions: geen aandoening, neurologische werking van anesthesie; Anesthesia; loss of consciousness

• Registration Number: NL-OMON36679
• Lead Sponsor: niversiteit van Amsterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

-Male, aged between 18-30 years;-corrected to normal vision;-Written informed consent.;-Screening for fMRI;-Psychiatric Screening;-Screening contra indications S-Ketamine

Exclusion Criteria

- Inability to speak Dutch or English;- Drug or alcohol abuse over a period of six months prior to the experiment;- History of closed-head injury;- With respect to MRI imaging: claustrophobia; presence of non-removable metal objects, use of psychotropic medication.;- Multiple serious drug allergies;- Use of psychopharmaca.;- Serious neurological or psychiatric disorders;- Recreational psychotrope drugs or psychoactive drugs use in the past 30 days;- Colour blindness;

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p> (a) fMRI, BOLD activation patterns, (b) cognitive task performance (visual<br /><br>short-term memory, motion induced blindness, backward masking)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>nvt</p><br>