The effect of Pluchea indica (L.) Less. tea on blood glucose and lipid profile in people with pre-diabetes, a randomized clinical trial

Phase 1

Completed

• Conditions: Pre-diabetes mellitusDyslipidemia; anti-hyperglycemia; anti-dyslipidemia investigation

• Registration Number: TCTR20191215002
• Lead Sponsor: Suranaree University of Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-15
• Study Completion: 2020-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Pre-diabetes age between 20 and 60 years. The pre-diabetes was diagnosed followed American Diabetes Association by Fasting Blood Sugar (FBS) 100 mg/dl (5.6 mmol/L) to 126 mg/dL (6.9 mmol/L) or Blood sugar 2h post-prandial 140 mg/dL (7.8 mmol/L) to 199 mg/dL (11.0 mmol/L) or HbA1c between 5.7-6.4% (39-47 mmol/mol)

Exclusion Criteria

(1) coronary heart diseases, e.g., heart failure, myocardial infarction, arrhythmia; (2) endocrine disease, e.g., sex gland disorder, thyroid disorder, and pituitary disorder; (3) pregnant or lactating women; (4) taking medications or supplements and herbs that might have interfered with blood glucose and lipid measurements. Participants were excluded if they had side effects of tea.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A single administration of tea on acute glucose tolerance 1 day Oral glucose tolerance testing

Secondary Outcome Measures

Name	Time	Method
ipid Profile 12 weeks after treatment TC, LDL-C, TG, HDL-C,Toxicity testing 12 weeks after treatment Blood toxicology (BUN, Creatinine, ALT, ALP, and CBC)