Comparison of Preoperative Nebulisation with Magnesium Sulphate And Dexmedetomidine for Hemodynamic Response to laryngoscopy and Endotracheal Intubation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Hemodynamic response to intubation by evaluation of heart rate, systolic BP, diastolic BP, mean BP.
研究概览
简要总结
Modern Anaesthesia is safe, balanced and of utmost importance to improve surgical outcome. So, it is essential to decrease the incidence and severity of anaesthesia related complications. Laryngoscopy and endotracheal intubation are associated with hemodynamic response which is characterized by increase in heart rate and blood pressure. These transient responses are normally harmless in healthy people, but can be dangerous in patients with reactive airways, hypertension, coronary artery diseases, cerebrovascular disorders. So, all efforts are made to decrease hemodynamic response in patients undergoing general anaesthesia with endotracheal intubation.
Numerous drugs such as opioids, beta blockers and intravenous lignocaine are used to attenuate this hemodynamic response.
The study is conducted to compare the incidence of preoperative nebulisation with magnesium sulphate and dexmedetomidine for hemodynamic response to Laryngoscopy and endotracheal intubation
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.ASA 1 and 2 2.General anaesthesia requiring Endotracheal intubation 3.Informed consent.
排除标准
- 未提供
结局指标
主要结局
Hemodynamic response to intubation by evaluation of heart rate, systolic BP, diastolic BP, mean BP.
时间窗: At baseline, After intubation,2 min ,5 min,10 min
次要结局
未报告次要终点
研究者
DrVenkatesh Soundarya
Sapthagiri Institute Of Medical Sciences And Research Centre